Trigeminal neuropathy in connective tissue disease

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[Trigeminal neuropathy and connective tissue diseases].

Connective tissue diseases are a rare and poorly understood etiology of trigeminal neuropathy. In a retrospective multicentric study covering 12 years. 12 cases were identified in the archives of the Departments of Neurology, Rheumatology and Internal Medicine: 4 were associated with progressive systemic sclerosis. 4 with mixed connective tissue diseases and 4 with Sjögren's syndrome. In 9 of t...

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B cell Therapy to Treat an Axonal Neuropathy in Mixed Connective Tissue Disease

The B cell is a vital contributor to humoral immunity. The B cell-specific antigen CD20 is expressed during B cell development, starting at the pre-B cell level and persists through B cell differentiation, but is lost during terminal differentiation to plasma cells. Rituximab is a monoclonal antibody that destroys both normal and malignant B cells that have CD20 on their surfaces and is ther...

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Trigeminal sensory neuropathy and mixed connective tissue disease: A case report

Mixed connective tissue disease (MCTD), a multisystem disorder, has features of systemic lupus erythematosus, scleroderma, and polymyositis/dermatomyositis but also a high titer of antibody to ribonucleoprotein. A 62-year-old Japanese woman with MCTD had an isolated trigeminal sensory neuropathy as an early manifestation of MCTD. Raynaud’s phenomenon occurred almost simultaneously with the neur...

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b cell therapy to treat an axonal neuropathy in mixed connective tissue disease

the b cell is a vital contributor to humoral immunity. the b cell-specific antigen cd20 is expressed during b cell development, starting at the pre-b cell level and persists through b cell differentiation, but is lost during terminal differentiation to plasma cells. rituximab is a monoclonal antibody that destroys both normal and malignant b cells that have cd20 on their surfaces and is therefo...

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[Mixed connective tissue disease].

Mixed connective tissue disease deserves to be a distinct disease entity due to the persistent citation of this disease in the literature since the original description by Sharp in 1972, in spite of the presence of several criticisms against the independency of this disease. The characteristic features of mixed connective tissue disease are: 1) the presence of anti-U1snRNP antibody with high ti...

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ژورنال

عنوان ژورنال: Japanese Journal of Clinical Immunology

سال: 1987

ISSN: 0911-4300,1349-7413

DOI: 10.2177/jsci.10.71